abstract |
(57) [Summary] General formula (I): [In the general formula (I), A 1 represents an aromatic group, R 1 represents a hydrogen atom or —COCH 2 COC n F 2n + 1 , and n is 1 Represents an integer of from 6 to 6. The labeled probe represented by the formula (1) is bound to a probe such as a nucleic acid, a nucleic acid binding protein, a small molecule ligand or a ligand receptor, and a labeled substance is allowed to react with a target substance on a biological sample. A method for analyzing a target substance, which comprises measuring the fluorescence of a complex, a labeled nucleic acid probe and a labeled nucleotide. [Effect] Disadvantages such as interference of fluorescence and low sensitivity due to contaminants can be eliminated. Further, it is possible to provide an analysis method using a labeled probe that can be used on a living tissue. |