http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1282726-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6769cf5b10a46403ab68c20d26d3640 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-255 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-255 |
| filingDate | 1996-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddfe15e8175430343ac1683a61af1c87 |
| publicationDate | 1998-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IT-1282726-B1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF 4- (6-METHOXY-2-NAFTIL) -2-BUTA- NONE |
| abstract | Preparation of 4-(6-methoxy-2-naphthyl)-2-butanone (I) (Nabumetone) comprises condensing 6-methoxy-2-naphthaldehyde with furfuryl acetoacetate, followed by the hydrogenolysis and decarboxylation of the resulting 3-furfuryloxycarbonyl-4-(6-methoxy-2-naphthyl)-3-buten-2-one (II). Preferably the condensation is carried out in the presence of basic catalysts, preferably piperidinium acetate. The hydrogenolysis is carried out in the presence of palladium-on-charcoal, and directly on the condensation reaction mixture, without recovering compound (II). |
| priorityDate | 1996-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.