http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1209127-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1cd6051bf69f25a0652ded4e4edac31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-70 |
| filingDate | 1979-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7ed0fede66709ef498df0005387783b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10d24848d9d6ab0ecbcb055f4b90e7b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37db594d1b14843a34a714d2932ea6d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ae839a4b5394f813aa24209fd3c9ed |
| publicationDate | 1989-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IT-1209127-B |
| titleOfInvention | NITROGEN HETEROCYCLIC DERIVATIVES THERAPEUTIC ADAPTITY, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES |
| abstract | Heterocyclic cpds. of formula (I) and their pharmaceutically acceptable derivs. are new. (where one adjacent pair of R5-R8 gps. forms a -CZC(G1)=C(G2)-Z- chain, and R4,R9 and the other R5-R8 gps. are H, halogen, alkyl, alkenyl, NO2, NR1R2, OR3, S(O)nR3, or alkyl substd. by OH, NH2, alkoxy or carbonyloxy(sic). n=O, 1 or 2. R1 and R2 are H alkyl, CONHR3, or phenyl opt. substd. by alkyl or halogen, or NR1R2 is a 5- or 6-membered heterocyclic gp. R3 is H, alkyl alkenyl or phenyl. One of G1 and G2 is H and the other is E. where E is COOH, tetrazol-5-yl or a gp. of formula: where R10 and R11 are H, alkyl, alkenyl, phenylalkyl, alkanoyl or alkoxycarbonyl, provided that R10 is H when R11 is H. Each Z is independently O or S. One or two of a-d are N and the others are C, with the proviso that when a=b=c=C and d=N, R4 cannot be OH para to the N atom when (i) E is ortho to the N atom and comprises COOH, tetrazol-5-yl or unsubstd. (tetrazol-5-yl) carbamoyl, (ii) R9=H, (iii) G1=H and G2=E, (iv) R5-R8 are H, halogen, OH, alkyl, alkenyl, alkoxy or NR1R2 and (V) either Z gp. is O). Cpds. (I) are antiallergic agents useful for treating a wide range of disorders associated with antigen-antibody reactions or excessive mucus secretion. |
| priorityDate | 1978-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.