http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1135358-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G- |
filingDate | 1981-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1986-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9da5f4b3506bce94c076684eea8271dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52d9a4030e3d25ea3350168c5594212 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa094b96d42bacd3f1bf55fe1cd47c96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb97844af4aa232152f51e0d989a200f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4de3c24d39f5269af2cbeedcec6e7fb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44c550e8495a381500808a16ff153912 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b0b1c4943d4dfbd0db45efa608843b |
publicationDate | 1986-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IT-1135358-B |
titleOfInvention | PROCEDURE FOR REGULATING THE PRODUCTION OF ALCALOIDS IN FERMENTATION PROCESSES |
abstract | A process is claimed for regulating the amt. and proportions of alkaloids obtained by culturing mutant strains of Claviceps purpurea which produce principally ergocornine (Ia), alpha- ergocryptine (Ib) and beta-ergocryptine (Ic). The process comprises using a cpd. which acts as a precursor for isoleucine biosynthesis, or which stimulates isoleucine formation by biochemical control, as a regulator during conventional fermentation. The regulator can be methyloxalacetic acid, alpha-ketobutyric acid, threonine, homoserine, homocysteine and/or methionine. It can be used in an amt. of 0.01-10 (pref. 0.05-5.0) g/l. The proportions of (Ic) can be increased to the level required for prodn. of dihydroergotoxine, which is used as the (m)ethanesulphonate for treatment of peripheral and cerebral circulatory disorders. |
priorityDate | 1981-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.