http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1101455-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a7ebd2ce5ef7e691bd44c48a88a2bfc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1978-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1985-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IT-1101455-B |
| titleOfInvention | NEUROMUSCULAR BLOCKING AGENTS |
| abstract | Tetrahydroisoquinolinium salts of formula (I) are new. In (I) each of B and C is a gp. of formula (II): where m is 2-4 C is para or meta to B. n is 2-4. Each of R1-7 is H or 1-4C alkoxy. Y is 1-4C alkyl. X- is a pharmaceutically acceptable anion. One at least of R1-4 is alkoxy and >=1 of R5-7 is alkoxy). (I) are neuromuscular blockers which relax striated muscle during surgery or tracheal intubation. They combine the short-term effect of depolarising blockers with the reduced side-effects of non-depolarising blockers. A typical cpd. is the dichloride of bis 3- N-methyl-1-(3,4,5-(MeO)3benzyl -6,7-(MeO)2-1,2,3,4-tetrahy- droisoquinolinium propyl m-phenylene-3,3'-dipropionate. |
| priorityDate | 1978-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.