http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1098319-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- |
filingDate | 1978-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1985-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1985-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IT-1098319-B |
titleOfInvention | DERIVATIVES OF 2-AMINO-CYCLOPEN-1-ENE-1 DYTHIOCARBOXYLIC ACID AND PROCEDURE FOR THEIR PREPARATION |
abstract | 2-Aminocyclopentane-1-thiocarbonyl disulphides (I) and their physiologically acceptable salts are new. In (I), R is H or 1-6C alkyl (opt. substd. by 1-4C alkoxy, OH, CO and/or amino); 2-4C alkenyl, 3-8C cycloalkyl, or phenyl. (I) are dopamine-beta-hydroxylase inhibitors and have antihypertensive and antiparkinsonism activity. (I) have lower toxicity than known dopamine-beta-hydroxylase inhibitors. A typical prod., 2-allylamino cyclopentene-1-thiocarbonyl disulphide, is prepd. in 84.4% yield by the H2O2 oxidn. of 2-allylaminocyclopentene-1-dithiocarboxylic acid. |
priorityDate | 1978-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.