http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-1086287-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_583c45ad08b627ee5c50e09f1d2bf96a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1977-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1985-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IT-1086287-B |
| titleOfInvention | METAMPICILLIN LYSINATE AND METHOD FOR ITS MANUFACTURE |
| abstract | New methampicillin-lysine adducts (methampicillin lysinate) are of formula (I): (where M is H or a metal e.g. Na, K, Ca or Al). (I) are active against Gram-positive and -negative bacteria. They have the advantage of water-solubility without loss of chemical stability. The water-solubility of (I) permits various liq. dosage forms to be formulated. (I) have very high absorption rates in the gastro-intestinal tract. In an example, methampicillin L-lysinate (i.e. (I; M = H) derived from L-lysine) is prepd. by adjusting an aq. suspension of ampicillin to pH 7-8 with NaHCO3, adding aq. formaldehyde, and L-lysine, and acidifying to pH 2.5-3.0 with HCl. |
| priorityDate | 1977-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.