| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate |
2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_835e2293c5dcaba81155016ecfc87be3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6925e7ed0dc37d2a72850a20b66ff604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eef17356e11cee304d73534396dc0407 |
| publicationDate |
2015-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
IN-2014DN03447-A |
| abstract |
The present invention relates to an improved method for preparing l-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7- methoxyquinazolin-6-yloxy)piperidin-l-yl)-prop-2-en-l-one hydrochloride, which selectively and effectively inhibits the growth of cancer cells induced by over-expression of an epidermal growth factor receptor (EGFR) and prevents the development of drug resistance caused by mutation of a tyrosine kinase, and intermediates used therein. |
| priorityDate |
2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |