abstract |
The present invention relates to an improved in-situ process for the preparation of Valsartan intermediate, N-[2'-(lH-tetrazol-5yI) biphenyl-4-yl) methyl] N-valeryl-(L)-valine benzylester. More particularly, the present invention relates to an improved, cost effective and industrially feasible in-situ process for the preparation of Valsartan intermediate, N-[2'-(IH-tetrazol-5yl) biphenyl-4-yl) methyl] N-valeryl-(L)-valine benzylester from L-valine. |