http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-44145-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbbb31e7315b8accd6544acf506c2d88 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D321-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B67-38 |
filingDate | 1974-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1977-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IL-44145-A |
titleOfInvention | Dioxatricyclodecanes and their production |
abstract | 1436821 4 - Hydroxy - 2,9 - dioxatricyclo [4,3,1,0<SP>3,7</SP>]decanes KALI-CHEMIE PHARMA GmbH 18 Jan 1974 [8 Feb 1973] 02548/74 Heading C2C Novel compounds I in which R 1 is C 1-4 alkyl, R 2 is OCOR 4 or OCONHR 5 when R 3 is hydrogen and R 3 is OCONHR 5 when R 2 is hydrogen (R 4 is C 1-4 alkyl and R 5 is a C 1-6 alkyl, C 2-6 unsaturated aliphatic, C 3-6 cycloaliphatic or aromatic group) and the 10,11 bond may be hydrogenated are prepared by reducing a compound III in which the 10,11 bond may be hydrogenated preferably with a metal hydride to form a mixture of the corresponding 4α- and 4#- hydroxy compounds and reacting the 4α-OH compound with a carboxylic acid chloride R 4 COCl, a carboxylic anhydride (R 4 CO) 2 O, an isocyanate R 5 NCO, an ester or chloride of a carbamic acid R 5 NH-COR 6 (in which R 6 is chlorine or alkoxy) or with phosgene followed by an amine R 5 NH 2 to form compounds I (R 3 =H): compounds I (R 3 = OCONHR 5 ) are prepared from the corresponding 4#-hydroxy compound by the methods described above. Compounds I have sedative, hyprotic and narcotic properties and may be administered orally or parenterally.n[GB1436821A] |
priorityDate | 1973-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.