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filingDate 1998-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IL-127129-A
titleOfInvention Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared
abstract A method for preparing a tablet for the vaginal administration of progesterone for systemic use, comprising the steps of: slowly mixing water with micronized progesterone, the total amount of water mixed with said micronized progesterone not exceeding the maximum wetting capacity of the amount of micronized progesterone, whereby to obtain wetted micronized progesterone; drying said wetted micronized progesterone to a humidity content of substantially 0%, whereby to form substantially dry micronized progesterone; mixing said substantially dry micronized progesterone with a pharmaceutically acceptable excipient or diluent therefor and optionally an effervescent; forming a tablet by direct compaction of said substantially dry micronized progesterone which has been mixed with said pharmaceutically acceptable excipient or diluent therefor.
priorityDate 1998-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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