http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-126839-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_977ebb660999f345084ffad260515ff6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 |
| filingDate | 1998-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IL-126839-A |
| titleOfInvention | History of indolyl-pyrrolidinemethylpyrol, process for their preparation and pharmaceutical preparations containing them |
| abstract | An immunosuppressive compound which is a (1H-indol-2-yl) -5 [(2H-pyrrol-2-ylidene) methyl] -1H-pyrrole derivative of the formula wherein each of R1, R2, R3 and R4, which are the same or different, independently represent hydrogen, C1-C6 alkyl, halogen, cyano, nitro, hydroxy, C1-C6 alkoxy unsubstituted or substituted by phenyl, C1-C6 alkyl-carbonyloxy, -NRaRb in which each of Ra and Rb independently is hydrogen or C1-C6 alkyl, C1-C6 alkyl- carbonylamino, carboxy, (C1-C6 alkoxy) carbonyl, aralkyl-carbamoyl, arylcarbamoyl or -CONRcRd in which each of Rc and Rd independently is hydrogen or C1-C6 alkyl, or Rc and Rd, taken together with the nitrogen atom to which they are linked, from a morpholino or piperidino ring; R5 represents halogen, hydroxy or C1-C11 alkoxy unsubstituted or substituted by phenyl; and R6 represents hydrogen, C2-C20alkanoyl, C3-C20 alkenoyl, phenyl, C1-C20 alkyl or C2-C20 alkenyl, wherein the alkanoyl, alkenoyl, alkyl and alkenyl groups are each unsubstituted or substituted by 1 to 3 substituents chosen independently from halogen, C1-C6 alkoxy, hydroxy, aryl, aryloxy, cyano, carboxy, (C1-C6 alkoxy) carbonyl, (C3-C4 alkenyl) carbamoyl, aralkyl-carbamoyl, arylcarbamoyl and -CONRcRd wherein Rc and Rd are as defined above; or a pharmaceutically acceptable salt thereof. 3558 כ" ו בכסלו התשס" ג - December 1, 2002 |
| priorityDate | 1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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