| abstract |
A particle consisting of a solid dispersion comprising (a) itraconazole, or one of its stereoisomers, or a mixture of two or three or four of its stereoisomers, and (b) one or more pharmaceutically acceptable water-soluble polymers that have an apparent viscosity of 1 to 100 mPa.s when dissolved in a 2% aqueous solution at 20!C solution, said particle having a particle size of less than 600 e and wherein the weight-by-weight ratio of (a): (b) is in the range of 1:1 to 1:17. |