http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-118143-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be8d6cfb14d04522568dd6146ad713a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e76c7e164e39ffb25408c1555d5818e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
filingDate | 1996-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IL-118143-A |
titleOfInvention | Preparation of recanidipine hydrochloride |
abstract | A process for the preparation of methyl 1,1,-N-trimethyl-N- (3,3-diphenylpropyl)-2- aminoethyl 1,4-dihydro-2,6- dimethyl-4- (3-nitrophenyl)-pyridine-3,5- dicarboxylate (lercanidipine) hydrochloride, the process comprising: (a) halogenating 2,6-dimethyl-5- methoxycarbonyl-4-(3-nitrophenyl)-1,4- dihydro-pyridine-3- carboxylic acid with a halogenating agent in an aprotic solvent; (b) adding 2, N-dimethyl-N- (3,3-diphenylpropyl)-1- amino-2-propanol dissolved in an aprotic solvent to the resultant acid halide; and (c) isolating the resultant lercanidipine as its anhydrous hydrochloride. 1309 כ" ג בסיון התשס" א - June 14, 2001 |
priorityDate | 1995-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.