| abstract |
Compounds selected from the group consisting of: 3a-hydroxy-3b-(3'-methyl-but-3'-en- 1'-ynyl)-5b-pregnan-20-one; 3a-hydroxy-3b-(3'-methyl-but-3'-en- 1'-ynyl)-5a-pregnan-20-one; 3b-(cyclopropyl)ethynyl-3a -hydroxy-5.45-pregnan-20-one; and 3a,21-dihydroxy-3b-fluoromethyl-5a- pregnan-20-one; or physiologically acceptable 3-esters, 20-esters, 21-esters, 3,20-diesters, or 2263 ו' באלול התשס" ב - August 14, 2002 3,21-diesters thereof, 3a, 21-dihydroxy-3b-trifluoromethyl- 19-nor-5b-pregnan-20-one, 21 -hemisuccinate, sodium salts; 3a, 20a-dihydroxy-21-methyl-5a-pregnane, bis hemisuccinate; 3a, 21-dihydroxy-3b-ethenyl-5a- pregnan-20-one, 21-ahemisuccinate, 3a,21-dihydroxy-3b-trifluoromethyl-5b- pregnan-20-one, 21 hemifumarate sodium salt; 3a,21-dihydroxy-3b-trifluoromethyl-5b- pregnan-20-one, methyl 21-succinate; 3a,21-dihydroxy-3b-trifluoromethyl-5b- pregnan-20-one, 21-propionate; bis (3a,21-dihydroxy-3b- trifluoromethyl-5b-pregnan-20-one) 21-hemisuccinate; and bis (3a21-dihydroxy-3b-ethynyl-5b- pregnan-20-one) 21-hemisuccinate. |