| abstract |
Compounds of the formula ONYS ONHO wherein Y is CHOR; R is H, (C1-C9) phenylalkyl, phenyl or alkoxyalkyl of the formula -(CH2)nO(CH2)mCH3, n is 0, 1, 2, 3 or 4; m is 2, 3 or 4; pharmaceutically acceptable cationic salts thereof; and pharmaceutically acceptable acid addition salts thereof; with the proviso that when R is H, the compound is either (1S)-5-£4-(3-(5-methyl-2-phenyl- 4-oxazoly)-1-hydroxypropyl) benzyl| thiazolidine-2, 4-dione, substantially free of its corresponding 1R enantiomer, or the compound is (1R)-5-£4-(3-(5-methyl- 2-phenyl-4-oxazolyl)-1-hydroxypropyl) benzyl| thiazolidine-2,4-dione, substan- tially free of its corresponding 1S enantiomer. |