http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-S86947-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_714b6ef357f52ec6f207341a3b5cb7a3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-00 |
| filingDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfbdcebee949afc799f970402c8ffb9a |
| publicationDate | 2019-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-S86947-B2 |
| titleOfInvention | Blood circulation diagnosis medication o-sulfonamide benzoic acid synthesis method |
| abstract | Blood circulation diagnosis medication o-sulfonamide benzoic acid synthesis method, comprises thetfollowing steps:3 mol 2-benzene sulfonamide-6-bromo-isophenone and 4-5 mol ethylene glycol monoisopropyl ether were added to the reaction vessel, controlled the stirring speed of 130-160 rpm for 30-40 min, and then raise the temperature of the solution to 40-50 °C, 5-6 mol tetrabutyl titanate was added to the reaction vessel by 5-8 times, which was added every 20-30 min, the temperature was controlled at the 55-60 °C, it was maintained for 130-150 min, then the temperature is reduced to 10-13 °C, the solid is precipitated, filtered and washed with the potassium bromide solution, the pH of the solution is adjusted to 4-5, then the solid is precipitated again, filtered, and washed with the dipropylamine solution, and washed with the dichlorobenzene solution, recrystallizated in ether solution, got the finished o-sulfonamide benzoic acid. |
| priorityDate | 2018-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.