http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-S20180079-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff640cd055f847a62331cd8048ca2636 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-00 |
| filingDate | 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e30814e3b9a9658a321a34516a94b968 |
| publicationDate | 2019-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-S20180079-A2 |
| titleOfInvention | Medicine intermediates 2,6-dicarboxylic acid pyridine synthesis method |
| abstract | Medicine intermediates 2,6-dicarboxylic acid pyridine synthesis method, comprises the following steps: 2 mol 2-isopropyl-3,5-dihydroxy-6-ethylpyridine and5-7 mol ethylene glycol methyl ether were added to the reaction vessel, controlled the stirring rate at 190-230 rpm, raised the temperature to 60-67 V, added 3-4mol bismuth trichloride, kept for 40-60 min, reduced the temperature of the solution to 5-9 V, precipitated the solid, filtrated, washed with potassium nitrate solution for 3-7 times, combined the filtrate and washing solution, controlled the stirring speed at110-130 rpm, adjusted the pH to 2-3 by oxalic acid solution, washed with N-benzylmethylamine solution, washed with benzyl methyl ether solution, recrystallized in propyl phenyl ketone solution, precipitated the crystals, got the finished product 2,6-dicarboxylic acid pyridine. |
| priorityDate | 2017-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.