http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-960761-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a39aaf1151602e8695bd3d1879b45561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef984517ad4fa88458ab2a9b88ab9961
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
filingDate 1996-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f44987cadf4e66ecc10c39ef7af1e1
publicationDate 1998-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-960761-A1
titleOfInvention Combinations for use in increasing the potency of a¹substrate for multidrug resistance related protein
abstract A combination of an agent which is a substrate for multidrug resistance related protein (MRP) and an inhibitor of MRP which is a non-steroidal anti-inflammatory drug (NSAID) or a structural analogue thereof for simultaneous, sequential or separate use for increasing the potency of the substrate. The substrates include anti-cancer drugs and transition metal complexes. The combinations can be used to overcome the resistance to MRP substrates exhibited in many conditions, such as resistance to chemotherapy where patients have developed resistance, especially as a result of MRP over-expression to their chemotherapy.
priorityDate 1996-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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