http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-960232-A1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00
filingDate 1996-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04266f6e6a5d3a998c76f0ed3ce40bae
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publicationDate 1997-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-960232-A1
titleOfInvention Manufacture of steroids
abstract Tixocortol pivalate is manufactured on an industrial scale by forming a sodium salt to thiopivalic acid in a closed reaction vessel 1. The sodium salt is then reacted with an appropriate hydrocortisone derivative to form the pivalate. The thiopivalic acid is charged through an inlet line 4 into a container 2 which is housed in an enclosed fume tent 15 with a sealable entry door flap 14 and an outlet 16 to a scrubber. The inlet line 4 is then closed and a vacuum is drawn on the line 5 and a delivery line 20 from the reaction vessel 1. A valve 8 is then opened and the acid is drawn into the vessel 1. When the container 2 is emptied, acetone is used to wash any residual acid and the wash is also drawn into the vessel 1, cleaning the delivery line 20.
priorityDate 1996-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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