http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-920307-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03627f82d4edc6567f9627df6efdde5d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00 |
| filingDate | 1992-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1992-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-920307-A1 |
| titleOfInvention | Precipitation-induced asymmetric transformation of chiral¹alpha-amino acids and salts thereof |
| abstract | The present invention provides a method for resolving a mixture of optically active isomers of an alpha -amino acid to obtain the preferred optically active isomer. The mixture of isomers is contacted with at least one chiral resolving agent in an organic acid, which is at least a partial solvent for the alpha -amino acid, and in the presence of a mineral acid, which is present in a quantity which does not protonate the NH2 functionality of the alpha -amino acid to an extent that diastereomer interconversion is substantially prevented, and in the presence of a catalytic amount of an aromatic aldehyde. The contacting results in simultaneous resolution of a desired diastereomer and interconversion of the remaining undesired diastereomer, to provide a very high yield of the desired diastereomer having a very high optical purity. |
| priorityDate | 1991-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.