http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-912113-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J73-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 |
| filingDate | 1991-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1992-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-912113-A1 |
| titleOfInvention | NOVEL 17ß-HYDROXYBENZOYL-4-AZA-5Ó-ANDROST-1-EN-3-ONES AS¹TESTOSTERONE REDUCTASE INHIBITORS |
| abstract | Novel 17 beta -hydroxybenzoyl-4-aza-5 alpha -androst-1-en-3-ones as testosterone reductase inhibitors of the formula: wherein R is selected from hydrogen, methyl and ethyl and R<2> is phenyl substituted with one or more of: -OH, -OC1-C4 alkyl, C1-C4 alkyl, -(CH2)mH, -(CH2)n COOR, including protected -OH, where m is 1-4, n is 1-3, and providing C1-C4 alkyl is only present when one of the above oxygen containing radicals is present, wherein the dotted line represents a double bond which can be present, pharmaceutically acceptable salts and esters thereof, and a pharmaceutical formulation thereof. The above compounds are active as testosterone reductase inhibitors and thus are useful topically for treatment of acne, seborrhea, female hirsutism, and systemically in treatment of benign prostatic hypertrophy. h |
| priorityDate | 1990-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.