http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-910318-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c51ea0deadb0c18cfc9815d86bc9507e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
| filingDate | 1991-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1991-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-910318-A1 |
| titleOfInvention | New cis-platinum complexes with chelating amines and¹sulphinyl carboxylates |
| abstract | Platinum (II) complexes of formula (I) where: Am is a monodentate amine, or (Am)2 is a bidentate amine, B represents a straight or branched alkyl residue or a single bond, R is selected from the group of hydrogen, (C3-C8) cycloalkyl, phenyl or naphthyl which may be substituted by halogens (I, Br, Cl, F), trihalomethane, hydroxyl, (C1-C4)-alkoxyl, (C1-C7)-acylamino, (C1-C7)-sulphamido, allyl, phenoxyl, haloalkoxyl, nitro, cyano, azido, with condition that when R is hydrogen B is different from a single bond, Q is a residue of formula -(CH2)n1-CRaRb-(CH2)n2-, 1,2- or 2,3-naphthalene, benzo-1,3-dioxolan-5,6-diyl, substituted or unsubstituted 1,2-phenylene, Ra and Rb are selected independently of each other from the group of hydrogen, allyl, linear or branched (C1-C8)-alkyl, -(CH2)pOH, -(CH2CH2O)q-CH3, or taken together with the carbon atom to which they are bonded form a (C3-C8) cycloalkyl, or heterocyclic tetrahydropyran-4,4-diyl, n1 and n2 are independently zero or the integer 1, p is an integer from 2 to 6, and q is an integer from 1 - 3, X<-> is a biocompatible anion such as chloride, bromide, iodide, nitrate, perchlorate, or one equivalent of sulphate or phosphate, or an anion of a monovalent C1-C4 organic acid such as acetate, propionate or chloroacetate, or of an aromatic acid such as benzoate, or of a heteroaromatic acid such as nicotinate are described. The compounds are useful as anti-tumour drugs. |
| priorityDate | 1990-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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