http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-904496-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-01 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-182 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-22 |
filingDate | 1990-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-904496-A1 |
titleOfInvention | Indolocarbazoles from saccharothrix aerocolonigenes subsp.¹copiosa subsp. nov. scc 1951, atcc 53856 |
abstract | The indolocarbazoles represented by formula (I) wherein Ra and Rb are each H or Ra and Rb taken together are A or B wherein R1 and R2 are independently H or OH or OCH3 and R3 is OH, NHCH3, NCH3 COCH3 or NHCOCH3 and R4 is OH or H and, stereochemical isomers thereof or pharmaceutical compositions thereof useful for inhibiting myosin light chain kinase, protein kinase C or tumor cell proliferation as well as producing an antihypertensive effect and an anti-inflammatory effect in warm-blood animals such as man are disclosed with the provisos that (1) when Ra and Rb together are A, and R1=H or OH, R3 is not NHCH3; (2) when Ra and Rb together are B, then R1=R4=H; (3) when Ra=Rb=H R1=-OCH3, and (4) when Ra and Rb taken together are A, and R1=H, R3 is not (II). |
priorityDate | 1989-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 412.