abstract |
HMG-CoA reductase-inhibiting imino-substituted pyridines of the formula <IMAGE> (I) in which R1 is optionally substituted aryl, R2 is optionally substituted aryl or alkyl, OH, alkoxy, aralkoxy, or optionally substituted aryloxy, R3 is cycloalkyl, or optionally substituted aaryl or alkyl, R4 is alkyl or cycloalkyl, X is -CH2-CH2- or [CH=CH-, R is <IMAGE> R6 is H or alkyl, and R7 is H, alkyl, phenylalkyl, aryl or a cation, and their salts.n[US5064841A] |