| abstract |
Salts of phenylpiperazines of formula I wherein R represents hydrogen, halogen, trifluoromethyl, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, amino, C1-C6-alkanoylamino or C1-C6-alkanoyloxy in association with acid compounds of the formula II wherein X represents a hydrogen atom, a hydroxy group, an amino group, a protected amino group or, together with the hydrogen atom on the carbon, an oxo group and R1 represents hydrogen, a phenyl radical, an indolyl-(3)-methyl radical, an imidazolyl-(4)-methyl radical, a C1-C10-alkyl group or a C1C10-alkyl group that is substituted by one or two hydroxy groups, a carboxy group, a phosphono group (-PO3H2), a C1-C6-alkoxy group, a mercapto group, a C1-C6-alkylthio group, a phenyl group, a hydroxyphenyl group, a C2-C6-alkanoylamino group or a C1-C6-alkoxycarbonyl group wherein the hydroxy groups present may also be esterified by phosphoric acid.n[CA2008683A1] |