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filingDate 1987-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1988-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-873498-L
titleOfInvention Purification of recombinant beta-interferon incorporating¹rp-hplc.
abstract RP-HPLC methods for purifying recombinant beta-interferon are disclosed that employ wide-pore, silica gel reverse-phase high performance liquid chromatograph (RP-HPLC) columns and solvent systems containing acetonitrile as the organic modifier and either heptafluorobutyric acid or trifluoroacetic acid as the organic acid. The invention concerns processes for purifying recombinant IFN- beta incorporating this RP-HPLC method. The products may be formulated for pharmaceutical or veterinary use.n[EP0274900A2]
priorityDate 1986-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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