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filingDate 1986-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1987-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-861894-L
titleOfInvention Chemical compounds
abstract Vitamin D analogues represented by general formula (I), in which formula X stands for hydrogen, lower alkyl, halogen or hydroxy; Y stands for hydrogen or hydroxy; R<1> and R<2>, which may be the same or different, stand for lower alkyl, optionally substitutedwith halogen or hydroxy with the proviso that R<1> and R<2> cannot both be methyl when X is other than lower alkyl, or, taken together with the carbon atom numbered 25, R<1> and R<2> can form a saturated or unsaturated C3-C9 carbocyclic ring which may optionally be substituted at any possible position(s) with lower alkyl, halogen or hydroxy; R<3> stands for hydrogen or lower alkyl; R<4> and R<5> represent either each hydrogen, or when taken together constitute a bond, with the result that a double bond connects carbon atoms numbered 22 and 23; and bioreversible derivatives thereof. The compounds of the invention have a favourable therapeutic index and are particularly useful in the treatment of human and veterinary disorders which are characterized by abnormal cell proliferation and/or cell differentiation.n[WO8700834A1]
priorityDate 1985-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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