http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-850476-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C62-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J73-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 |
| filingDate | 1985-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-850476-L |
| titleOfInvention | Androst-1-en-3-one derivatives |
| abstract | 17 beta -N-monosubstituted carbamoyl or 17 beta -acyl-4-aza-5 alpha -androst-1-en-3-ones of the formula: <CHEM> in which R is hydrogen, methyl or ethyl; R<2> is a C1-12 straight or branched alkyl radical or a monocyclic aryl optionally containing one or more methyl or ethyl substituents and/or one or more Cl, F or Br substituents; and in Formula IA R<2> may also be benzyl, phenethyl, 2-pyridyl, 4-pyridyl, 2-pyrrolyl, 2-furyl or thiophenyl; R min is hydrogen or methyl; R sec is hydrogen or beta -methyl and in Formula IA may also be alpha -methyl; and R''' is hydrogen, alpha -methyl or beta -methyl and pharmaceutical formulations containing the above compounds are active as testosterone 5 alpha -reductase inhibitors and thus are useful topically for treatment of acne, seborrhoea and female hirsutism, and systemically in the treatment of benign prostatic hypertrophy.n[EP0155096A2] |
| priorityDate | 1984-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.