http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-841974-L
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 1984-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1985-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-841974-L |
titleOfInvention | Fast release solid preparations of a dihydropyridine |
abstract | PURPOSE:To provide the titled drug preparation composed of a solid solution containing dihydropyridine-A substance and hydroxypropylmethylcellulose, and having remarkably improved solubility in water and transferability to blood. CONSTITUTION:The objective easily-soluble solid preparation can be procuced by dissolving the dihydropyridine-A substance of formula in an organic solvent such as chloroform, adding hydroxypropylmethylcellulose which is a water- soluble polymer to the solution to obtain a uniform mixture, and removing the organic solvent. The compound of formula has vasodilating activity such as coronary vasodilation action and hypotensive action, etc. and is useful as a remedy for coronary vessel diseases such as cardiac insufficiency, stenocardia, myocardial infarction, etc. and for hypertension. The amount of hydroxypropylmethylcellulose is at least to enable to form a dispersion of the dihydropyridine-A substance, preferably 3-7pts.wt. of hydroxypropylmethylcellulose per 1pt.wt. of dihydropyridine-A substance.n[JP60038322A] |
priorityDate | 1983-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.