http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-840230-L

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60442fdc20fd71481fc3d6b8cdee2c31
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
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filingDate 1984-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1984-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-840230-L
titleOfInvention Azetidinones.
abstract N-(Mono- or disubstituted methyl)-2-azetidinones, produced by cyclizing 9-hydroxy or a-halo substituted acid sec-amides in which the amide nitrogen is subsituted with a mono- or di-substituted methyl group having activating substituents, are useful intermediates for the production of antibiotics. The compounds have the formula <CHEM> in which R is hydrogen, C1-C4 alkoxy, amino, protected-amino, acylamino, diacylamino, C1-C4 alkyl, or C1-C4 alkyl sustituted by hydroxy, C1-C4 alkoxy, halogen, amino, protected-amino, carboxy, or protected carboxy; R1 is hydrogen, hydroxy, C1-C4 alkoxy, halogen, or C1-C4 alkyl; R2 is hydrogen, phenyl, substituted phenyl, carboxy, C1-C4 alkoxycarbonyl, protected carboxy, sulfvdryl, C1-C4 alkylthio, C2-C4 alkanoylthio, halogen, C1-C4 alkoxy, C1-C4 alkyl, or C1-C4 alkyl substituted by hydroxy, C1-C4 alkoxy, halogen, amino, protected amino, carboxy, or protected carboxy; Y is a substituted methyl group of the formulae <CHEM> in which R3 or R3 min is hydrogen, C1-C4 alkoxycarbonyl, protected carboxy, carboxy, C1-C4 alkylsulfonyl, arylsulfonyl, C1-C4 alkylsulfinyl, arylsulfinyl, C1-C4 alkanoyl, aroyl, C1-C4 alkyl, cyano, vinyl, or ethinyl; R4 is hydrogen, C1-C4 alkyl, or a carboxy protecting group; R5 and R5 min , independently are C1-C4 alkyl, C1-C4 alkoxycarbonyl, carboxy, protected-carboxy, or phenyl; and, R6 is hydrogen, C1-C4 alkyl, C1-C4 alkoxy-carbonyl, protected-carboxy, or phenyl; or an addition salt thereof.n[EP0116432A2]
priorityDate 1983-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 31.