| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-443
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate |
1983-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1984-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
IE-832063-L |
| titleOfInvention |
1-pyridyloxy-3-indolyalkylamino-2-propanols |
| abstract |
1-(Pyridinyloxy)-3-(indolylalkylamino)- 2-propanols, novel cardiovascular agents having vasodilator activity and a range of adrenergic beta-receptor blocking action, are prepared by any one of three routes that comprise a novel general process. The general process comprises coupling a hydroxyl- or halogen- substituted pyridine with a suitable halogen- or hydroxyl-substituted propanol or incipient propanol intermediate; and the products of these couplings are also novel. In the preferred of the three coupling routes, product 1-(pyridinyloxy)-3-(indolyl- alkylamino)-2-propanols are formed directly; in the other two coupling routes further processing of the coupling products is required to form the 1-(pyridinyloxy)-3-(indolylalkylamino)- 2-propanols. Preferred compounds bear an amide or cyano substituent in the 3-position of the pyridine ring.n[GB2126230A] |
| priorityDate |
1982-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |