http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-792222-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86 |
| filingDate | 1979-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-792222-L |
| titleOfInvention | Azathiabicycloheptane derivatives |
| abstract | This invention relates to 7-oxo-4-thia-1-aza-bicyclo-[3,2,0]-heptane derivatives, to processes for their synthesis from esters of penicillanic acid 1-oxide, and to intermediate compounds obtained in the synthesis. More particularly, the present invention relates to new and novel compounds of formula (1): <IMAGE> (1) wherein R is a hydrogen atom, an alkyl having from 1 to 5 carbon atoms, trichloroethyl, benzyl, p-nitrobenzyl, diphenylmethyl, acetoxymethyl, pivaloyloxymethyl, phthalidyl, trimethylsilyl or a group of formula <IMAGE> and R1 is -CH2OH, -CH2OCOR2, -CH2OR3, -COOR2, -CHO, -CH2SH, -CH2SR4, -CH2NH2, -CH2NHCOR2 in which R2 is an alkyl having from 1 to 5 carbon atoms, aryl, aralkyl or a five- or six-membered heterocyclic ring containing one or more heteroatoms; R3 is an alkyl having from 1 to 5 carbon atoms, benzyl, trityl, trialkylsilyl; and R4 is a five- or six-membered heterocyclic ring containing one or more heteroatoms, benzyl, trityl or trialkylsilyl; and to the synthesis of such compounds. Compounds of formula (1) (E+Z isomers) are endowed with antibacterial activity.n[US4331677A] |
| priorityDate | 1978-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.