| abstract |
The compounds have the general Formula: <IMAGE> wherein Ar is phenyl or naphthyl, each X is an optional substituent independently chosen from a range of cyclic and non-cyclic aromatic and non-aromatic substituents, including alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, alkanyl, alkylsulphinyl, alkylthio, alkanamido, C3 to C6 optionally alkyl substituted cycloalkyl, optionally alkyl substituted cycloalkyl alkyl, each having up to 8 carbon atoms, phenyl, trifluoromethyl, nitro and cyanoalkyl, n indicates the number of X substituents and is from 0 to 2, and Het represents a nitrogen heterocycle, optionally containing one further hetero atom and optionally substituted with up to two ring substituents which are alkyl, N-lower alkyl carboxamido, N,N-dilower alkyl carboxamido, carbalkoxy wherein each of said foregoing groups contains up to 8 carbon atoms, oxo, or carboxamido.n[GB2001633A] |