| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc4209078d025bee83bc1ad02a70fcf2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-182 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate |
1991-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec7a4bc2a7dffb04e723060b7e135e7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7146938d80badb33d71867e478aa46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dda8db76785f537efd2e8fbaee322bb3 |
| publicationDate |
1995-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
IE-65891-B1 |
| titleOfInvention |
Preparation of non-recemic furo[3,4-c]pyridine derivatives |
| abstract |
Non-racemic furo[3, 4-c]pyridine derivatives I wherein R3, R'3, R4 and R6 represent various substituents are prepared by subjecting a compound II or III wherein R7 represents an acyl group up to C18 to the action of an esterase capable of hydrolysing either the (+) or the (-) enantiometic form of the selected compound. The hydrolysed and unhydrolysed compounds are then separated. If compound II is selected, this gives one enantiomer of compound I; the other enantiomer can be obtained by de-esterifying the unhydrolysed compound. If compound III is selected, the hydrolysed compound is deprotected/cyclised to give one enantiomer of the compound I; the unhydrolysed compound is de-esterified and deprotected/cyclised to give the other enantiomer. The preferred esterase is alpha -chymotrypsin. |
| priorityDate |
1990-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |