http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-57517-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0613 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
| filingDate | 1984-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1992-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-57517-B1 |
| titleOfInvention | Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride |
| abstract | alpha -L-aspartyl-L-phenylalanine methyl ester and its hydrochloride are prepared by a process which comprises dissolving alpha -L-aspartyl-L-phenylalanine dimethyl ester in a methanol/hydrochloric acid mixture solvent which contains, when hydrochloric acid es expressed in terms of concentrated hydrochloric acid and water, 0 to 10% by volume of methanol, 8 to 55% by volume of concentrated hydrochloric acid and water (balance) to give a solution in which the concentration of said ester is from 0.01 mol/dl to 0.3 mol/dl; holding said solution at 0 to 60 DEG C to crystallize out the formed alpha -L-aspartyl-L-phenylalanine methyl ester as its hydrochloride; isolating said hydrochloride; and obtaining, when required, the free ester by neutralization with an alkali. The ester prepared by this process is useful as a sweetener. |
| priorityDate | 1983-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.