http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-55577-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-87 |
| filingDate | 1983-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1990-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-55577-B1 |
| titleOfInvention | Penicillanic acid dioxide prodrug |
| abstract | A compound of the formula <IMAGE> is a prodrug of 4,4-dioxopenicillanic acid, wherein R is hydrogen or methyl; R1, R2 and R3 (a) when taken individually are each alkyl containing one to four carbon atoms, or (b) when taken together with the nitrogen to which they are attached form a five- or six-membered saturated monocyclic moiety, an eight-membered saturated bicyclic moiety or a five- or six-membered aromatic cyclic moiety annulated with zero, one or two fused benzene rings, with the proviso that any R1, R2 or R3 not part of a cyclic moiety is alkyl containing one to four carbon atoms; and X- is a pharmaceutically-acceptable anion. The prodrug can be included with a beta-lactam antibiotic in a pharmaceutical composition which can be employed in the treatment of infection in mammals. The above-described compounds hydrolyze in vivo to 4,4-dioxopenicillanic acid.n[US4428935A] |
| priorityDate | 1982-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.