http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-47073-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 |
| filingDate | 1978-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1983-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-47073-B1 |
| titleOfInvention | Alpha amino-acids, compositions and process for preparing said compounds |
| abstract | alpha -Amino Acids, compositions and process for preparing said compounds alpha -ethynyl- and - alpha -vinyl-3,4-disubstituted pheynylalanines and esters thereof, have been prepared by reaction of methyl 3,4-dihydroxybenzoate with diphenyldichloromethane, reduction of the so obtained methyl 3,4-diphenylmethylene- dioxy- benzoate to 3,4-diphenylmethylenedioxybenzyl- alcohol, and transforming this to the benzylchloride. This 3,4-diphenylmethylenedioxybenzylchloride reacts with 1-trimethyl- silyl-N-benzylidene-3-aminoprop-1-yne to form 3-(3,4- diphenylmethylenedioxybenzyl) -1-trimethysilyl N-benzylidene-3- aminoprop-1-yne. …With methyl chloroformate this compound gives 3-carbomethoxy-3- (3, 4- diphenylmethylenedioxybenzyl-1-trimethylsilyl-N-benzylidene -3-aminoprop-1-yne. …The benzylidene-group, the trimethylsilyl-group and the diphenyl-methylene- group are removed, which results in the formation of alpha -ethynyl- 3,4-dihydroxy- phenylalanine. The alpha -vinyl- analog is obtained by hydrogenation of an intermediate. The compounds have a pharmaceutical activity. |
| priorityDate | 1977-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.