http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-46963-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 |
| filingDate | 1978-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1983-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-46963-B1 |
| titleOfInvention | Imidazo-isoquinoline-diones |
| abstract | Imidazol 4,5-h isoquinoline-4,6-dione derivs. of formula (I) and their acid-addn. salts are new. In (I) R1 is lower alkyl, phenylalkyl, 3-6C cycloalkyl, or phenyl opt. mono- or disubstd. by halogen, OH, MeO, MeS, MeSO, MeSO2 and/or benzyloxy; A is H or (CH2)nNR2R3; R2 is H or lower alkyl and R3 is lower alkyl and R3 is lower alkyl opt. substd. by dimethoxyphenyl, or NR2R3 is piperidino, morpholino or 4-alkyl-1-piperazinyl; n=2 or 3. (I; A=H) are cardiotonic agents, hypotensives and blood platelet aggregation inhibitors; (I; A=(CH2)nNR2R3) are antiarrhythmic agents. In an example a typical cpd. (I; A=H, R1=Ph) is prepd. from 4,4-dimethyl-7-acetamido-2H,4H-isoquinoline-1,3-dione. |
| priorityDate | 1977-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 229.