http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-46954-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 1978-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1983-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-46954-B1 |
| titleOfInvention | New pregn-4-ene derivatives,processes for preparing them and pharmaceutical compositions containing them |
| abstract | Novel DELTA 4-pregnenes of the formula I wherein X1 is selected from the group consisting of =O and Y is selected from the group consisting of hydrogen and halogen, R1 is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms, X2 is selected from the group consisting of hydrogen and -OH, R in the 16 alpha - or beta -position is selected from the group consisting of hydrogen, -OH and methyl, Z is selected from the group consisting of (1) -OH, (2) alkoxy of 1 to 12 carbon atoms, (3) cycloalkoxy of 3 to 12 carbon atoms, (4) acyloxy of an organic carboxylic acid of 1 to 18 carbon atoms, (5) wherein W is a hydrocarbon of 1 to 12 carbon atoms, (6) wherein R2 is hydrogen or alkyl of 1 to 12 carbon atoms, (7) wherein R3 is a hydrocarbon of 1 to 12 carbon atoms and (8) the dotted line in the A ring indicates the optional presence of a double bond in the 1(2)-position and A and B are both hydrogen or A is methyl, chlorine or fluorine while B is hydrogen or A and B may form a double bond in the 6(7)-position with the proviso that if the A ring has a 1(2) double bond, A is hydrogen or fluorine, B is hydrogen, Y is hydrogen or fluorine, X2 is hydrogen or -OH, R is methyl and Z is not -OH having a very marked antiallergic activity with a reduced anti-inflammatory activity and a process for their preparation. |
| priorityDate | 1977-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.