http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-46269-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-00 |
| filingDate | 1977-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1983-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-46269-B1 |
| titleOfInvention | Isoxazole derivatives,process for their manufacture and preparations containing these compounds |
| abstract | Novel 5-methylisoxazole-4-carboxamides of the formula I are prepared in which R denotes a mono-, di- or trinuclear, unsaturated heterocyclic radical having 3 to 13 carbon atoms and one, two, three or four hetero atoms from the group comprising oxygen, sulphur and nitrogen, where at most one of the hetero atoms is other than nitrogen, in the ring system, which radical is unsubstituted or ring-substituted one, two or three times by C1-C3-alkyl, C1-C3-alkoxy, halogen, nitro, hydroxyl, carboxyl, carbamoyl or oxo, and their physiologically tolerable acid addition salts, by reaction of corresponding carboxylic acid derivatives, namely the corresponding acid halides, esters or anhydrides, with amines of the formula H2N-R. The compounds of the formula I are distinguished in particular by anti-inflammatory, antipyretic and analgesic properties combined with low toxicity and good gastric tolerability. |
| priorityDate | 1976-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.