http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-45833-L

Outgoing Links

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filingDate 1977-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1978-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber IE-45833-L
titleOfInvention N-quinolizinyl (or indolizinyl) benzamides.
abstract Compounds of the formula (I), and their pharmaceutically acceptable salts: <IMAGE> (I) wherein: R1 is a C1-6 alkoxy group; R2 and R3 are the same or different and are hydrogen, halogen, CF3, hydroxy, C1-6 alkoxy, C2-7 acyl, amino, amino substituted by one or two C1-6 alkyl groups, C2-7 acylamino aminocarbonyl or aminosulphone optionally substituted by one or two C1-6 alkyl groups, C1-6 alkylsulphone or nitro groups; X is either a nitrogen atom, in which case m+n is 3 to 5, m is 2 to 4, n is 1 to 3; or X is CH in which case m+n is 2 to 5, m is 1 to 5, and n is 0 to 4; p is 0 to 3; R4 is hydrogen, C1-6 alkyl, phenyl or phenyl-C1-6 alkyl, either of which phenyl moiety may be substituted by C1-6 alkyl, C1-6 alkoxy, CF3 or halogen, and R5 is hydrogen; or R4 and R5 are attached to two adjacent carbon atoms and form together with these two carbon atoms a fused benzene ring, which benzene ring may be substituted by C1-6 alkyl, C1-6 alkoxy, CF3 or halogen; are useful for treating disorders of the gastro-intestional function and for treating emesis.n[US4213983A]
priorityDate 1976-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 33.