http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-45171-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 |
| filingDate | 1977-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1982-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-45171-B1 |
| titleOfInvention | Pyrrolidine and pyrroline derivatives |
| abstract | Heterocyclic compounds of the formula in which R<1> is 2-thienyl or is phenyl which is substituted by a lower tertiary amino group, R<2> and R<3> are, independently of one another, hydrogen or lower alkyl and R<4> is phenyl which can be substituted by halogen, lower alkyl, lower alkoxy or primary, lower secondary or lower tertiary amino, where R<1> is phenyl substituted by a lower tertiary amino group if R<4> is phenyl or halogen-substituted phenyl, are prepared by reducing a compound of the formula or an N-oxide of a compound of the formula II. It is furthermore possible for a phenyl group R<4> to be converted by nitration into a nitrophenyl group; resulting bases can be converted into acid addition salts; resulting mixtures of cis and trans isomers can be fractionated, and resulting racemates can be resolved into the optical antipodes. The products have an analgesic activity and can be used to control pain. |
| priorityDate | 1976-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.