| abstract |
1520197 Tetracycline compositions containing 2-pyrrolidone PFIZER INC 15 Dec 1976 [2 Jan 1976] 52394/76 Heading A5B A stabilised antibiotic composition comprises a solution of a chelated tetracyclin in aqueous 2-pyrrolidone, the tetracycline being selected from oxytetracycline, doxycycline, tetracycline, chlortetracycline, and the pharmaceutically acceptable acid addition salts thereof. The chelates may be those of magnesium and/or calcium. The solution may also contain 1-7% by weight of polyvinylpyrrolidone of average molecular weight of ca. 5,000 to 100,000. |