http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-43582-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 |
| filingDate | 1976-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-43582-L |
| titleOfInvention | Desoxystreptamine derivatives |
| abstract | 1502537 2 - Desoxy - streptamine derivatives ROUSSEL-UCLAF 23 July 1976 [23 July 1975] 30746/76 Heading C2C Novel N 1 - [L(-) - 2 - hydroxy - 4 - aminobutyryl] - 4 - O - [2<SP>1</SP>,6<SP>1</SP> - diamino - 2<SP>1</SP>,6<SP>1</SP> - didesoxy - α,D - glucopyranosyl] - 6 - O - [3<SP>11</SP>- methylamino - 3<SP>11</SP>,4<SP>11</SP>,6<SP>11</SP> - tridesoxy - α,D- xylohexopyranosyl] - 2 - desoxystreptamine (I) and addition salts thereof with mineral or organic acids are prepared by reacting 4-O- [2<SP>1</SP>,6<SP>1</SP> - diamino - 21,61 - didesoxy - α,D - glucopyranosyl] - 6 - O - [3<SP>11</SP> - methylamino - 3<SP>11</SP>,4<SP>11</SP>, 6<SP>11</SP> - tridesoxy - α,D - xylohexopyranosyl] - 2- desoxystreptamine with N - benzyloxycarbonyloxy-succinimide, reacting the resulting novel 4 - O - [21 - amino - 61 - benzyloxycarbonylamino - 2<SP>1</SP>,6<SP>1</SP> - didesoxy - α,D - glucopyranosyl] - 6 - O - [3<SP>11</SP> - methylamino - 3<SP>11</SP>,4<SP>11</SP>, 6<SP>11</SP> - tridesoxy - α,D - xylohexopyranosyl] - 2- desoxystreptamine with the N-hydroxysuccinimide ester of L-(-)-γ-benzyloxycarbonylamino - α - hydroxy - butyric acid and catalytically hydrogenating the resulting novel N 1 - [L - (-) - 2 - hydroxy - 4 - benzyloxycarbonylamino - butyryl] - 4 - O - [2<SP>1</SP> - amino- 61 - benzyloxycarbonylamino - 2<SP>1</SP>,6<SP>1</SP> - didesoxy- α,D - glucopyranosyl] - 6 - O - [3<SP>11</SP> - methylamino - 3<SP>11</SP>,4<SP>11</SP>,6<SP>11</SP> - tridesoxy - α,D - xylohexopyranosyl] - 2 - desoxystreptamine, followed optionally by salification with an appropriate acid. Pharmaceutical compositions having antibiotic activity comprise, as active ingredient, the compound (I) or a pharmaceutically acceptable mineral or organic acid addition salt thereof, in association with a suitable pharmaceutical vehicle.n[GB1502537A] |
| priorityDate | 1975-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.