http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-41837-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c2e77fb1df82e0112f5d9de2502809 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
| filingDate | 1975-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-41837-B1 |
| titleOfInvention | 7-aminocephalosporanic acid and derivatives thereof |
| abstract | Compounds of the formula: in which X is hydrogen, azido or -YR1, Y is oxygen or sulphur and R1 is lower alkyl, acyl or a heterocyclic radical, and Z' is hydrogen or an ester radical, are prepared from corresponding compounds of the formula: in which R is acyl and Z is hydrogen or the residue of a mixed anhydride or of an ester. To do this, the starting material is reacted with an agent which forms imino halide in the presence of an amine under anhydrous conditions, and the reaction product is reacted with an anhydrous alkanol; the resulting 1-deoxy-7-imino ether compound is then subjected to acid hydrolysis. The hydrolysis simultaneously unblocks the 4-carboxyl group when Z is a mixed anhydride or a readily hydrolysable ester. The compounds are intermediates for the preparation of antibiotics of the cephalosporin series. |
| priorityDate | 1974-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.