http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-41657-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c2e77fb1df82e0112f5d9de2502809 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 |
filingDate | 1975-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1980-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | IE-41657-B1 |
titleOfInvention | New cephalospirin esters |
abstract | 1512660 Cephalosporin esters SANGYOKAGAKU-KENKYUKYOKAI 28 Aug 1975 [29 Aug 1974 14 April 1975] 35520/75 Heading C2C The invention comprises compounds of formula wherein A is acylamino; Y is S or S#O; X is H or C 1-6 alkoanoyloxy; R1 is aryl, aralkyl or C 1-6 alkyl or alkoxy; and R2 is C 1-6 alkyl, R1CO or R 3 R 4 NCO, where R 3 and R 4 are each H, aryl or C 1-6 alkyl, or R3R4N forms a heterocyclic ring or R2 may be H when Y is S#O. These compounds are prepared by heating in an inert solvent in presence of a catalyst, the analogous penicillin ester S-oxide, and if desired (a) making the cephem S-oxide by conventional oxidation of unoxidized product and/or (h) brominating the product and treating the 3-bromomethyl compound with an alkanoic acid salt to give the compound where X is alkanoyloxy. The above esters are converted to the corresponding acids by treatment with HNO 2 or a derivative thereof. |
priorityDate | 1974-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.