http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-41488-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 |
| filingDate | 1975-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-41488-B1 |
| titleOfInvention | D and 1-cyanocyproheptadine compositions containing it and methods of using it |
| abstract | (-)-1-Methyl-4-(3-cyano-5H-dibenzo[a,d]cyclohepten-5-ylidene)piperi dine and (+)-1-methyl-4-(3-cyano-5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidin e are prepared in virtually pure form. These compounds are obtained by preparing the diastereomeric salts of the corresponding (+/-)-racemate in suitable solvents using optically active acids. The (-)-form, which is virtually free of the (+)-form, is then removed by crystallisation. The salt obtained is then converted into the free base, and the (+)-form is isolated from the residue as the free base. The (+)-form of the base and also the corresponding acid addition salts can be used as peripheral and central anticholinergics. The (-)-form of the base including corresponding acid addition salts can be used as sedatives. |
| priorityDate | 1974-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.