abstract |
1464328 Esterification of amino acids MERCK & CO Inc 17 June 1975 [25 June 1974] 25799/75 Heading C2C Esters of organic amino carboxylic acids containing a single primary amino group are obtained by reacting the organic amino carboxylic acid with an alkylating agent containing the group wherein X is Cl, Br, I or a substituted -SO 3 - group, in an aprotic solvent. Specified aprotic solvents are dimethyl sulphoxide, dimethyl formamide, hexamethylphosphoramide, tetramethyl urea, acetonitrile and mixtures thereof. |