http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IE-41459-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-82 |
| filingDate | 1975-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | IE-41459-B1 |
| titleOfInvention | Benzothiazolyl ureas and pharmaceutical compositions containing them |
| abstract | The invention relates to novel N-2-(6-hydroxybenzothiazolyl)-Ν'-phenyl (or substituted-phenyl) ureas and a process for the preparation thereof. The ureas are useful as immune regulants. 5 The invention provides a compound of the formula z°\/\ S HO—yk/ V y Formula I wherein R is hydrogen, (C.j-C3) alkyl, (C^-C3) alkoxy or halo. 10 The invention also provides a process for preparing the compound of Formula I which comprises reacting a benzothiazole of the formula Γί>· AX Formula V with a substituted phenyl compound of the formula R —R 15 Formula VI wherein R is hydrogen, (C^-C^) alkyl, (C^-C^) alkoxy or halo; R1 and R2 are -N=C=0 or -NH2, R2 being -NH2 when R1 7 1 3 is -NCO and R being -NCO when R is -NH2; and R is ~SiCCH3)3 or R „ „ 0 V \ ” /O-NHC- and hydrolyzing the resulting compound. The invention further provides a pharmaceutical formulation containing a compound of Formula I associated with a pharmaceutically acceptable carrier therefor. |
| priorityDate | 1974-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.